1. God revealed Himself to Jacob in his loneliness, assuring him of His care.
Genesis 28:15
Behold, I am with you and will keep you wherever you go, and will bring you back to this land; for I will not leave you until I have done what I have spoken to you.
2. When Elijah became discouraged, he fled into the darkness of a cave. There, God spoke to him encouraging Him in his despondency.
1 Kings 19:9,11-15
And there he went into a cave, and spent the night in that place; and behold, the word of the Lord came to him, and He said to him, “What are you doing here, Elijah? Then He said, “Go out, and stand on the mountain before the Lord.” And behold, the Lord passed by, and a great and strong wind tore into the mountains and broke the rocks in pieces before the Lord, but the Lord was not in the wind; and after the wind an earthquake, but he Lord was not in the earthquake; and after the earthquake a fire, but he Lord was not in the fire; and after the fire a still small voice. So it was when Elijah heard it, that he wrapped his face in his mantle and went out and stood in the entrance of the cave. Suddenly a voice came to him, and said, “What are you doing here, Elijah?” And he said, “I have been very zealous for the Lord God of hosts; because the children of Israel have forsaken Your covenant, torn down Your altars, and killed Your prophets with the sword. I alone am left; and they seek to take my life.” Then the Lord said to him: “Go, return on your way to the wilderness of Damascus; and when you arrive, anoint Hazael as king over Syria.
3. God promises never to forsake His children.
Hebrews 13:5
Let your conduct be without covetousness; be content with such things as you have. For He Himself has said, “I will never leave you nor forsake you.”
4. Since Jesus was despised and rejected of men and left alone to die on the cross, He fully understands your loneliness.
Isaiah 53:3,4
He is despised and rejected by men, a Man of sorrows and acquainted with grief. And we hid, as it were, our faces from Him; He was despised, and we did not esteem Him. Surely He has borne our griefs and carried our sorrows; yet we esteemed Him stricken, smitten by God, and afflicted.
Isaiah 63:3,9
I have trodden the winepress alone, and from the peoples no one was with Me. For I have trodden them in My anger, and trampled them in My fury; their blood is sprinkled upon My garments, and I have stained all My robes. In all their affliction He was afflicted, and the Angel of His Presence saved them; in His love and in His pity He redeemed them; and He bore them and carried them all the days of old.
5. When you come to Jesus, He fills your heart with the glory of His own presence. He adopts you as His son or daughter.
2 Corinthians 6:16-18
And what agreement has the temple of God with idols? For you are the temple of the living God. As God has said: “I will dwell in them and walk among them, I will be their God, and they shall be My people” Therefore “Come out from among them and be separate, says the Lord. Do not touch what is unclean, and I will receive you. I will be a Father to you and you shall be My sons and daughters, says the Lord Almighty.”
6. When embarrassed and left alone through divorce or widowed by death, a Christian woman has assurance that God Himself will fill the womanly needs of her heart.
Isaiah 54:4-8
“Do not fear, for you will not be ashamed; neither be disgraced, for you will not be put to shame; for you will forget the shame of your youth, and will not remember the reproach of your widowhood anymore. For your Maker is your husband, the Lord of hosts is His name; and your Redeemer is the Holy One of Israel; He is called the God of the whole earth. For the Lord has called you like a woman forsaken and grieved in spirit, like a youthful wife when you were refused,” says your God. “For a mere moment I have forsaken you, but with great mercies I will gather you. With a little wrath I hid My face from you for a moment; but with everlasting kindness I will have mercy on you,” says the Lord, your Redeemer.
7. To come out of your loneliness, it becomes essential to invest your life in making others happy. To have friends, you must become a friend to somebody.
Proverbs 11:25
The generous soul will be made rich, and he who waters will also be watered himself.
Proverbs 18:24
A man who has friends must himself be friendly, but there is a friend who sticks closer than a brother.
